Sampling motifs on phylogenetic trees

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Sampling motifs on phylogenetic trees.

We present a method to find motifs by simultaneously using the overrepresentation property and the evolutionary conservation property of motifs. This method is applicable to divergent species where alignment is unreliable, which overcomes a major limitation of the current methods. The method has been applied to search regulatory motifs in four yeast species based on ChIP-chip data in Saccharomy...

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Billey et al. [arXiv:1507.04976] have recently discovered a surprisingly simple formula for the number an(σ) of leaf-labelled rooted nonembedded binary trees (also known as phylogenetic trees) with n ≥ 1 leaves, xed (for the relabelling action) by a given permutation σ ∈ Sn. Denoting by λ ` n the integer partition giving the sizes of the cycles of σ in non-increasing order, they show by a guess...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 2005

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.0501620102